to go through biotransformation;that is it goes through
metabolism within the body of the patients.
The drug is excreted from the body via bowel and the
renal tubules. Drugs that build up in the body system as a
result of excessive dosages , poor circulation ,faulty metabolism
or inadequate excretion may result in cumulative effects.
The drug half -life is defined as the amount of time
required for 50% of the drug to be eliminated by the
body.Drug given oral are altered by the first- pass effect.
Drug that trick an enzymes into binding to it
instead of the enzyme's normal targets cell produces
effect by which it is known as enzymes interaction.
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